AN EFFICIENT, ONE-POT TRANSAMIDATION OF 8-AMINOQUINOLINE AMIDES ACTIVATED BY TERTIARY-BUTYLOXYCARBONYL





Phase I/II study of the combination of panobinostat and carfilzomib in patients with relapsed/refractory multiple myeloma

The purpose of this study was to assess the safety and efficacy of the combination of panobinostat and carfilzomib in patients with relapsed/refractory multiple myeloma.Patients with multiple myeloma who had relapsed after at least one prior treatment were eligible to participate.In the dose escalation part of the study a standard 3+3 design was us

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